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  • Posted by $ WilliamShipley 2 weeks ago
    It is technically inaccurate on PCR tests. PCR analyzers run as many cycles as you want. If it fails to detect the target genetic code, it is false. If it does detect the code, you then determine at which cycle it was detected and use cutoff value to determine if it is clinically significant.

    If it is positive, it did detect the target, so it is technically positive. The clinical significance is more of a judgement call on where to set the threshold.

    If that is being set too high, then the issue a new number. The kits are just fine.
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    • Posted by freedomforall 2 weeks ago
      So its even easier to change the rate of positive results by a federal agency stipulating the maximum cycles allowed for reporting.
      They can also stipulate that co-morbidities will henceforth be reported as the true cause of deaths, not the virus.
      Voila! Buy-dem conquered the virus! All hail the conqueror!
      Oops, that can't happen until after the serfs are vaccinated. Wouldn't want to upset Pharma's big profits.
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      • Posted by $ WilliamShipley 2 weeks ago
        Yes, the test is accurate, you just need to understand the question you are asking. If the target DNA is not in the sample, you will never detect it no matter how many cycles you run.

        If you detect it, it is technically positive, but the important question of clinical significance is a judgement.
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  • Posted by Lucky 1 week, 6 days ago
    WilliamShipley is correct. The pcr test is very clever and very good, it won the Nobel for the inventor.

    That the Ct is important is also correct. So important that it is hardly ever (never) given with the test result!
    (..ie. detection Yes/No, and the sensitivity of testing was somewhere from a hundred to billions).

    The clinical significance is more of a judgement call Exactly.

    The pcr test is valuable for detection and tracking even extremely small amount of the virus (or whatever it is that is used as the comparison standard in that machine). It is next to useless for specifying whether a particular individual will get sick - unless the Ct is known and properly interpreted. This never happens.

    So the suggestion is, the Ct will continue to be never mentioned, but it will be lowered to give a reasonably reliable indicator. Over the next few months the number of cases drops. Therefore the new policy works. Easy.
    (Note- nothing in the real world changes, just the sensitivity of the tests, same number of infections, but the case count changes)

    I am of the opinion that this technique is already being for manipulation for reported 'cases'.

    What I don't know is - How easy is it to change the Ct?
    I'd imagine it would be changeable weekly on each machine.
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  • Posted by 25n56il4 2 weeks ago
    Oh I love these guys. Notice from the CDC. If you take a Covid test it could be a false positive, or it could be a false negative. Notify your insurance company if you test positive.
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    • Posted by 25n56il4 1 week, 6 days ago
      I have to tell you guys for real. I've been doing my own research on Covid19 and Fauci is a liar! This is one damn puny virus. They can't even definitely tell people if they have this crap. Both my granddaughters supposedly got it and their tests were 'unknown antibodies'. An 89 year old male friend came back 'asymptomatic'. I've had the flu four times and each time knew exactly what I had. Once I landed in the hospital.
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    • Posted by $ 1 week, 6 days ago
      I also get a kick out of the folks who vehemently defend the method of testing which was designed to NOT to be diagnostic. Oh well. Some things just cannot be fixed.
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