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The Lancet Rules Russian COVID-19 Vaccine "Safe And Effective"

Posted by freedomforall 2 weeks ago to Technology
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Trial results reported Friday by the Lancet, the British medical journal responsible for publishing some of the earliest research on the coronavirus, found that Russia's Gameleya Institute-developed SARS-CoV-2 vaccine is both effective and safe, though scientists cautioned that long-term study is still required.

The vaccine, the researchers found, produced an antibody response in all test subjects while causing no serious adverse effects. The results mark the latest stamp of legitimacy for the vaccine developed by the world-reknowned Gameleya Institute, and show how the early and intense skepticism expressed by some in the West might have been premature.
SOURCE URL: https://www.zerohedge.com/geopolitical/lancet-rules-russian-covid-19-vaccine-safe-and-effective


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  • Posted by Lucky 2 weeks ago
    Russians have a well earned reputation for brilliance in mathematics, aerodynamics and several other branches of science.
    When it comes to the often long boring slogging of quality control and assurance, testing, and the manufacture of reliable products, maybe, or not.
    Unfair stereotype? Yes but still.

    When a vaccine typically takes 3, 4, or 5 years to design, test, and produce, then I hear that the Russians have got one in production after six months, I think- include me out for a few years.
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    • Posted by 2 weeks ago
      I think they'd be a great ally and trading partner.
      They have a lot to offer, but I'm not sure they can trust us any more than we are able to de-program ourselves and trust them.

      I agree on the vaccine. I'd rather take HCQ and let the more gullible get the vaccines.
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      • Posted by term2 1 week, 3 days ago
        I agree that the russians could be a good trading partner, in spite of their ruthless behavior when it comes to their internal dissidents !!

        As to a vaccine, all it has to be is effective enough to keep you from falling ill with corona, an not have bad side effects. I am not sure that the normal that phase 3 trials give enough assurances of that, or actually give unnecessary assurances of it. So the Russians might be right after all. We will have to see
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    • Posted by $ WilliamShipley 1 week, 5 days ago
      It's really misleading to think about how long a vaccine "typically" takes when technology improves. The genome of the virus was determined and published in January, vaccine makers started with that before they even had samples.

      Normally you do Phase I, analyze the results, Phase II, analyze the results, Phase III, analyze the results get approval and begin production. The "Warp speed" program has overlapped the phases, planning and starting the next phase while still finishing the prior one. The vaccine is in production even though phase III is a bit over a month into it. Actually, I believe, there are three different vaccines in production -- so that if the are approved they will go out right away.

      And they are talking about due to an emergency that we separate safe from effective. If the vaccine is safe but we are not sure off how effective it is, it could be conditionally approved.

      I've always thought that if we needed an FDA (and those here would certainly challenge that), their mission should be limited to safe. The marketplace can deal with effective.

      I also know that many here, for good reasons, do not like vaccines. They do trigger the immune system and stuff can happen when you do that, but in this case, I'm ready to roll up my sleeve if we have one that seems safe and looks like it is generating a decent immune response.
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      • Posted by term2 1 week, 3 days ago
        I would agree. effectiveness is determined by the results in terms of preventing covid19 infections. Easy enough to figure that one and word will get out pretty fast if its NOT effective
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      • Posted by Lucky 1 week, 4 days ago
        I agree with most of that. Yes a lot has already been done, a lot can be speeded-up especially the regulatory form filling stuff. My concern is on how fast real human trials can be done, how many weeks, months or years do you wait before an adverse reaction can be be ruled out? You can test on one hundred subjects for one year, and all is ok. Does that mean that 20 people are ok for 5 years with that medication?

        Back last century I was in testing for reliability and life of electronic components. There was something called 'accelerated' life tests. The name had the right 'cache'. Then a claim is made that testing at 50C higher temperature over 6 months was the equivalent of operating conditions for 6 years, well there is some, weak, evidence for that.
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        • Posted by $ WilliamShipley 1 week, 4 days ago
          I remember in the 1960's and 1970's the computer technicians would vary the voltage to the high end and low end of the range to look for marginal components before they failed. They finally came to the conclusion they were creating more problems than they were preventing.

          The probability of a bad reaction to a vaccine decreases relatively rapidly through time. Yes, it's possible that you would be just fine but 20 year later have a reaction but not likely.

          We've now been several months since the small group of phase I subjects were injected and now there are thousands of phase III. Reactions seem typical, injection soreness, mild fever -- you are activating the immune system after all.

          I have some of the risk factors so when a vaccine that doesn't have unusual side effects and even seems to be working is available, I want it. Covid-19 does not seem like something I want to get immunity to by catching it and surviving.
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        • Posted by 1 week, 4 days ago
          What components were being tested, Lucky?
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          • Posted by Lucky 1 week, 2 days ago
            Yup about the same era as WS.
            Components- capacitors, resistors, diodes, transistors, and that ilk. But not inductors, transformers.., I think as these were not produced on the same scale. I was in civil aviation and recall that military planes got older inferior devices as the testing specified by the agencies took longer and was more stringent. There were ways around that I think. As well, for similar reasons, military equipment had a lifetime double or more that of civil stuff.
            As WS says, extrapolating from tests to life takes some thought and guessing. I suppose the basic ideas on safety testing are much the same in pharmaceuticals. Yes many processes can be speeded up, maybe you do not need to test for five years, or two, but how many? If there should be a bad reaction that takes six months to detect, and you test for three months, then what? The answer could be in individual risk analysis, but in this case I'd go for HCQ.
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            • Posted by 1 week, 2 days ago
              Thanks. We build stereo amplifiers for home entertainment and our goal is for them to last 20+ years. We have had very few part failures but its early in the product life so testing process is an interest.
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              • Posted by Lucky 1 week, 1 day ago
                20 year life should not be a problem, take care with switches. I could give a lecture, only 40-50 years out of date!
                You would know about the 'bathtub curve'.

                Way off topic but some good news-
                Stella Immanuel, the Texas doc originally from Nigeria, who joined front-line-doctors in saying- HCQ works and is safe, was accused of something or other in a complaint to the Texas Medical Board -- now cleared by the Board.
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    • Posted by $ Commander 2 weeks ago
      While I will agree with you on opting out of vaccination, a friend of mine spent over 15 years as an internal Fed regulatory compliance auditor for Ely Lilly. Her accounting for costs and time of development are 85% due to compliance regs.
      And these institutions are the ones that push the regs, in my opinion, to preclude equitable competition. IE: every level of cost of compliance must be accounted for as a "profitable" step toward production distribution. Similar in auto safety compliance testing.
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      • Posted by $ Abaco 1 week, 5 days ago
        It's like regulations in the financial industry. Doesn't work.
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        • Posted by term2 1 week, 3 days ago
          I used to make medical devices. Their 510(k) premarket regulation just said that the product had to be "essentially similar to one in existence previously (that started out at 1976 but I think got updated to 1990). The "good manufactuing practices" regulation basically said that IF there was some injury, blame would fall on the idea that the company didnt do something to prevent it from happening. Like getting a ticket for getting in an accident- blaming the driver for not avoiding it.
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        • Posted by $ Commander 1 week, 5 days ago
          Yeah...I see regulations as extensions of fear that prevent exposure to learning.
          Can't remember how many times I have heard "there's a law....", "this shouldn't happen"... and i ask; Have you ever seen one sheet of paper stop a bullet?
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  • Posted by $ Thoritsu 1 week, 3 days ago
    This is excellent!

    Personally, don't need it. Along with an overwhelming majority of people, we have a vaccine that can produce antibodies. It is called a well-functioning immune system, operating in a healthy body.

    Make the vaccine available to people who need it. Let people who are susceptible/compromised wear masks and hide out. Let the vast majority of people get back to life, which we should've done on day 1.

    Others being afraid does not compel me to servitude. However, others being afraid does ruin the economy. and compromise general happiness. This fear mongering is overblown, and stems from only two sources:
    1. Ignorant people, and
    2. Evil people parochially seeking to ruin the world, to ensure Trump is not re-elected, such that they gain power.
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    • Posted by 1 week, 3 days ago
      The longer this stonewalling and shutdown goes on, the more I become convinced that the Chinese created the virus intentionally, and released it intentionally because Trump showed he was going to protect Americans from the rest of the world, and outside the US, China had the most to lose. (Possibly a less damaging virus was released in China to give them deniability.) The Democrats have been proving how they would react to such a virus since 2016, and they are also to blame, imo, albeit perhaps not complicit in the planning.
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      • Posted by DrZarkov99 1 week, 2 days ago
        One thing not noted in American media was that the Chinese stopped travel from Wuhan to any other part of China, to contain the spread of the virus, while at the same time they sent over 100,000 workers from Wuhan to European factories, mostly in Italy.
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      • Posted by Lucky 1 week, 2 days ago
        From looking around, that idea cannot be easily dismissed.
        If it were planned, they would have well guessed the hysteria and the damage we are doing to ourselves. So much spying, many contacts, and good analysis too.
        My reading is that there were different mutations arriving in Europe than in N.America.
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      • Posted by $ Thoritsu 1 week, 3 days ago
        Plausible, or even put up to it by the evil totalitarians, with evidence showing visceral, unfounded drive to undermine his administration. No other president has been so attacked. I doubt Lincoln was as demonized by the Confederacy.
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        • Posted by 1 week, 3 days ago
          This is almost certainly an international attempt at election rigging. I wonder if Soros had any connection to or knowledge of the virus research, since he is clearly taking advantage of it.
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    • Posted by $ WilliamShipley 1 week, 3 days ago
      Vaccines can give that well-functioning immune system a peek at the foe before you experience a significant infection. Counting on building my immune reaction based on encountering the infectious version in the wild is more risk than I want to take.
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      • Posted by $ Thoritsu 1 week, 3 days ago
        I understand, but COVID is not smallpox or polio, and If given the choice, I'd take infection over what we've been compelled to do. This chicken shit flu is not killing me.

        The question is: "Do you support compelling me and countless other based on your own decision?"
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        • Posted by $ WilliamShipley 1 week, 3 days ago
          I don't want to compel anyone. Everyone should make their own decisions. This is not smallpox or polio, but it's not the flu either the hematology impact can be pretty serious. I have both high blood pressure and diabetes so I have the risk factors. My blood pressure medicine either makes it worse or protects me -- there is a clinical trial in progress to figure out which. We'll know next summer!

          I generally don't take flu shots because the mild side effects are generally about as bad as I get flu. On the other hand I got the whole set of pneumonia shots. Losing a 26 year old healthy employee to H1N1 back in 2009 made it clear to me just how useless modern medicine is if your lungs are full and you can't absorb oxygen.

          I'm taking 5000IU of D every day and am generally healthy. I told Jan that I couldn't remember the last time I was home sick. She reminded me of a serious gout attack that kept me home for several days -- and I replied "that was in the 1990's".
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  • Posted by term2 1 week, 3 days ago
    I dont care who develops an effective and safe vaccine. I would rather have that than the corona virus itself....
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    • Posted by $ Thoritsu 1 week, 3 days ago
      I'd pick in order:
      1) vaccination,
      2) being fortunate,
      3) CoronaVirus infection,
      4) acting like aliens have invaded our planet, cowering behind masks, hand sanitizer and proximity, sacrificing recreation and playing sports (care NOTHING about spectator sports) and destroying our economy.
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  • Posted by $ Olduglycarl 1 week, 6 days ago
    I wonder, did they really do it?...maybe so, they don't seem to be ruled by the dumb idiots we have here...it would seem to be in Russia's best interest to do well for it's people...in general, they are no real threat to power and Russia needs the best and most qualified to survive.

    Am I giving Russia too much credit here?
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  • Posted by CaptainKirk 1 week, 2 days ago
    When safe is measured in weeks...
    And effective is measured as developing anti-bodies.

    Meanwhile, Dr. Peter Attia had a fellow on to explain the difference between "antibodies" and "antibodies".

    There are 2 possible antibodies. The kind that TAG the virus for destruction/pickup/macrophages.

    And the kind that tag the SPIKE, which make it inert, because it can no longer get into our cells.
    (My summary, not all viruses have a spike protein, but the concept is the same, the TAG covers the part that enables it to enter our cells. This is the GOLD STANDARD antibody!)

    I am not sure we know which kind of antibodies these people are making.
    Also, this virus appears to be able to Trigger a Cytokine Storm. This means PRIOR Immunity, even from a Vaccine could trigger this. This is what hits people so hard the second time in Dengue Fever. It is ALSO WHY the first SARS vaccine development was STOPPED. Because it caused this in the monkeys who were then exposed to the live virus!

    We are PLAYING with Fire! Kudos to the scientists for hitting certain goals. Hopefully we are NOT too smart for our own good here...
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  • Posted by DrZarkov99 1 week, 3 days ago
    What I find ironic, and very hypocritical, is that the Democrats, who have consistently badgered and harassed the anti-vaxxers, are now pronouncing any vaccine produced under Trump's "Hyperspeed" vaccine program as unsafe, advising everyone not to take any vaccines produced under this program. Apparently, now that everything is viewed through a political lens, they see any Trump victory, whether it's lifesaving or not, as something to be avoided at all cost. They're willing to fight him to the last drop of your blood.
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  • Posted by BCRinFremont 1 week, 4 days ago
    Putin has established a dictatorial oligopoly. His rule is somewhat benevolent to those who agree with him. For those who don’t agree, poison is the preferred solution. At his best, he can screw up elections in the US. At his worst....Stalin, again?
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    • Posted by CaptainKirk 1 week, 3 days ago
      Interesting. He kicked out SOME of the Banksters.

      IMO, he is THEIR Trump. The majority of what he is doing is actually helping the average Russian. Albeit with a slight criminal bent...

      In Russian Politics, you either play for keeps or you are summarily destroyed/killed. I think he is playing for keeps.

      But having been there a few times, Russia has really been improving under his watch.
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