A Surprise Source of Life's Code

Posted by $ AJAshinoff 8 years, 8 months ago to Science
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Good article...there is always more to know, more to understand.
SOURCE URL: http://www.scientificamerican.com/article/a-surprise-source-of-life-s-code/


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  • Posted by philosophercat 8 years, 7 months ago
    For all of you who are interested in climate change consider a fact mentioned in the article-snowball earth. About 800 million years ago the earth was a snowball, almost all water was frozen except around volcanos and thermal vents etc. Where was life and why did it survive this calamity? I suspect that species evolved very quickly to this strange dark cold world and the genes of the survivors became excess as the world warmed and then overheated many times. The genes are not lost they are stored for when the world changes and they are needed again. Sooner or later we will see I suspect that these "orphan" genes are "survival" genes and as the world warms up in this interglacial period they will ensure the survival of most species quite nicely. There is no reason the genome should be configured just for the world as it exists today after 4.2 billion years of catastrophic change. Think of the mass extinctions and the genes for survival those species must have had especially the little nocturnal insect eating shrews that became man.
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  • Posted by Herb7734 8 years, 7 months ago
    Scientists keep trying to find order in apparent chaos. The more they learn, the more puzzled they become. They try to unify something that came out of nothing with properties that sprang into existence without anything preceding it. By and large, the majority seem to persist in the belief that "God does not play dice with the Universe" as Einstein put it. What if God was actually saying, that "There is no unity, no pattern, everything is random. Deal with it." If I were a scientist, perhaps I could express it in an equation. In any case, that would explain everything, including the mysterious gene, dark matter, dark energy, etc. So far, scientists have been unable to figure out lots of stuff in quantum physics, etc. but that hasn't stopped them from utilizing the parts the do understand for the benefit of mankind and best of all, their pockets.
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  • Posted by $ jbrenner 8 years, 8 months ago
    This article is consistent with the revolutionary changes sometimes observed in species adaptation.
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    • Posted by $ 8 years, 8 months ago
      Whats remarkable to me is the ceaseless amount of unknown all around and within us.

      "Certain genes, however, seem to defy that origin story. They have no known relatives, and they bear no resemblance to any other gene. They’re the molecular equivalent of a mysterious beast discovered in the depths of a remote rainforest, a biological enigma seemingly unrelated to anything else on earth."

      Remarkably they seem to emerge from Junk DNA is some capacity that defies contemporary understanding and lacks explanation.

      "Researchers are beginning to understand that de novo genes seem to make up a significant part of the genome, yet scientists have little idea of how many there are or what they do. What's more, mutations in these genes can trigger catastrophic failures. “It seems like these novel genes are often the most important ones,” said Erich Bornberg-Bauer, a bioinformatician at the University of Münster in Germany."

      Absolutely fascinating and wonder-filled at the same time.

      You work in a very exciting profession.
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      • Posted by $ WilliamShipley 8 years, 8 months ago
        That's one of the drums I beat on a regular basis: The unknown is not something far away or requiring expensive particle accelerators to find. The unknown is all around us in everyday objects and activities. Every choice that someone made to create a product we use had alternatives that weren't followed. Open your eyes and look.
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        • Posted by johnpe1 8 years, 7 months ago
          wonderful observation, William! . we should be in awe
          of the myriad things which we don't know enough about .....
          to call ourselves "well informed."

          and, by the way, where's Jan? . this subject would be
          a favorite of hers! -- j
          .
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        • Posted by Maritimus 8 years, 7 months ago
          Hello, W,

          "Every choice that someone made to create a product we use had alternatives that weren't followed."

          Of course, that is true. (Except that very often there are many more possibilities, rather than just two alternatives.) But the humans make those choices. They use not only all the test results and calculations, but also their intuitive inclinations, i.e. artistic parts of their personalities. If there are better choices, someone else usually finds them. That is, in my mind, the main reason why innovation and competition within a free trade market are so vitally valuable. This also touches on the fact that almost anything could be made better. But is there a buyer willing to cough up the cost of additional efforts in design and production?
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          • Posted by $ WilliamShipley 8 years, 7 months ago
            Well I didn't say two alternatives. I think that people have a tendency to follow up on the first thing they find that actually works. My suspicion is that there are far more unexplored options than are usually considered. But, that's just an opinion.

            I use that philosophy to encourage people who work for me to think beyond "what's usually done".
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            • Posted by Maritimus 8 years, 7 months ago
              I need to apologize. I looked it up and learned that at least in English "alternative" means more than one "other".

              I hope that those people work for themselves and work with you. A nitpicker's observation, I agree.

              EDIT: added missing word and replaced wrong word
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      • Posted by Maritimus 8 years, 7 months ago
        Hello, AJA,

        Somehow the name Junk DNA, even after I had heard it many times, sparked an idea I would like to submit to your judgment.

        The old expression: "use it loose it", I think, expresses a deep meaning of a property of living matter. Evolution and competition for survival eliminate what is not needed, it seems to me.

        So, I think "junk" anything in this contest just reveals our state of ignorance. We do not know the function of something, so we throw it on the junk pile. I smell a bit of arrogance and a bit carelessness. Would you agree?
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        • Posted by $ 8 years, 7 months ago
          I'm no expert. Jbrenner probably knows infinitely more than I do on this subject.

          But the article explains that junk DNA is a slang term that is used for "Certain genes, however, seem to defy that origin story. They have no known relatives, and they bear no resemblance to any other gene."

          Yes, it could be carelessness and yes it could be arrogance. It not my field and not my word. :)
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  • Posted by VetteGuy 8 years, 7 months ago
    One of my favorite Murphy's Laws of Technology:

    "We don't know one millionth of one percent about anything."
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    • Posted by mdant 8 years, 7 months ago
      This is so true when it comes to big picture things like the universe, life, and existence itself. I am 100% with you on that. I consider it a big cop put when people apply this to everything though and say that everything is "gray".

      By the way VetteGuy, what kind of corvette do you/have you owned? I have had a 79, 84, 96, and right now I have a 1982 Collectors Edition that I am planning on moddeing out with C4 suspension and a LS2 from a 2007 Corvette with 6 speed auto (Yea, I know that makes a lot of people upset but I like my cars to be daily drivers and for me there is nothing better than the style of the C3 with total modern everything under the skin).
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      • Posted by TheRealBill 8 years, 7 months ago
        Not VetteGuy but if we're going to virtual wave here, mine is a black 99 coupe set up for wicked autocross - and my "daily driver".

        But I am eyeballin the new one really heavilly.
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        • Posted by mdant 8 years, 7 months ago
          Cool, cars are meant to be driven so I appreciate daily drivers. They made a big hit with the styling of the new one. Best in decades in my opinion. I have not driven them but I am sure it is great. By the way, the Corvette Museum in Bowling Green, KY (across from the Corvette Plant) now also has a racetrack so you can run your vette there. I live in Kentucky so I am sure I will check it out before to long.
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      • Posted by VetteGuy 8 years, 7 months ago
        I probably shoulda put a smiley face on that one - it is intended as tongue-in-cheek ... but with just a sliver of truth as well.

        My Vette was an 88 with the 4+3 tranny, but it is gone now. I still have my 78 Camaro Z28 T-top 4-speed, though. Incidentally, I love your idea of the C3 with C4 driveline & suspension. I'm not a purist when it comes to Vettes.
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        • Posted by mdant 8 years, 7 months ago
          I really like the Camaro as well! My 84 corvette had the 4+3...novel idea but I ended up turning off the overdrive and just driving it as a 4 speed unless I got on the interstate.
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          • Posted by VetteGuy 8 years, 7 months ago
            I ended up with the same situation on my 4+3. In my case, I replaced the "digital disco dash" with regular round gauges, and the automatic function ceased to work, so I put a switch on the dash.
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